FN3K

Across TCGA patient cohorts, FN3K protein abundance is significantly associated with the RNA expression of many other genes, with 12,953 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible FN3K-associated genes across cancer lineages are RAB40B, HID1, and C1orf115. Each is linked with FN3K in more than 7 cancer types. Because this analysis shows association rather than direction, both FN3K-to-partner and partner-to-FN3K results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FN3K versus RAB40B in GBM, with a Pearson correlation of 0.69.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FN3K→partner) and Y-score (partner→FN3K) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RAB40B →	+0.735	+0.482	<.001	<.001	3	8
BRCA	HID1 →	+1.100	+0.419	<.001	<.001	3	6
GBM	C1orf115 →	+1.134	+0.429	<.001	.001	3	5
BRCA	SGK3 →	+1.003	+0.550	<.001	<.001	3	5
CCRCC	ALDH6A1 →	+0.771	+0.351	.001	<.001	3	5
BRCA	ACADSB →	+0.965	+0.386	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,953 associations by consensus.

FN3K vs RAB40B — GBM

Explore this scatter interactively →