FN3K

Across TCGA patient cohorts, FN3K mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FN3K-associated genes across cancer lineages are MEP, Melanocytes, and Neurons. Each is linked with FN3K in more than 1 cancer types. Because this analysis shows association rather than direction, both FN3K-to-partner and partner-to-FN3K results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MEP grouped by FN3K-low versus FN3K-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FN3K→partner) and Y-score (partner→FN3K) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MEP →	+0.028	+2.470	.035	.011	3	1
UCEC	Melanocytes →	-0.013	-3.531	.011	.003	2	1
UCEC	Neurons →	-0.020	-2.437	.027	.020	2	1
UCEC	Class-switched memory B-cells →	-0.063	-3.584	.022	.003	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

MEP by FN3K expression — UCEC

Explore this box plot interactively →