FMO3

Across TCGA cell cohorts, FMO3 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible FMO3-associated genes across cancer lineages are OR6J1 and OR52N5. Each is linked with FMO3 in more than 1 cancer types. Because this analysis shows association rather than direction, both FMO3-to-partner and partner-to-FMO3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR6J1 grouped by FMO3-low versus FMO3-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FMO3→partner) and Y-score (partner→FMO3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	OR6J1 →	+0.004	+4.643	<.001	.005	3	1
OVARY	OR52N5 →	+0.042	+5.196	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

OR6J1 by FMO3 expression — BLOOD_Lymphoma

Explore this box plot interactively →