Across TCGA pan-cancer cohorts, FMO10P RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of FMO10P’s most consistent transcriptional readouts.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where FMO10P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types FMO10P is over-expressed in tumor.
HNSC and BRCA are the cancer types where FMO10P tumor–normal differential expression is most reproducible.