FMN1

Across TCGA pan-cancer cohorts, FMN1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated FMN1 data layer compared with 22 for mass-spec protein and 12 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher FMN1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated FMN1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and PDAC show a favorable association.

LSCC, HNSC, and UCEC are the cancer types where FMN1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Median	II,III,IV	0.610	0.877	.012	15	view →
HNSC	OS	Quartile	III,IV	0.514	0.872	.008	11	view →
UCEC	DFS	Quartile	All	1.000	0.848	.017	10	view →
PDAC	DFS	Median	III,IV	0.883	0.480	.010	9	view →
LUAD	DFS	Quartile	III,IV	0.547	0.912	.030	6	view →
CCRCC	DFS	Tertile	All	0.874	0.673	.039	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

FMN1–LSCC (OS)

Open the LSCC breakdown →