FMN1

Across TCGA pan-cancer cohorts, FMN1 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of FMN1’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where FMN1 RNA is repressed in tumor relative to normal tissue. In most cancer types FMN1 is over-expressed in tumor, although a few such as LUSC and READ show the opposite, repressed pattern.

LUSC, READ, and CHOL are the cancer types where FMN1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FMN1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	Male	II,III,IV	−1.272	<.001	8	view →
READ	All	III,IV	−0.555	.014	6	view →
CHOL	All	All	+1.195	<.001	5	view →
STAD	Male	All	+0.848	<.001	5	view →
HNSC	Male	IV	−0.660	.014	5	view →
KIRC	Female	All	−0.615	.001	5	view →
COAD	All	All	−0.452	.002	5	view →
LIHC	All	All	+0.104	.043	3	view →
PRAD	All	All	+0.365	.011	2	view →
THCA	All	All	−0.266	.020	2	view →
BRCA	All	All	+0.260	.032	2	view →
KIRP	Male	All	−0.557	.009	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

FMN1–LUSC

Open the LUSC breakdown →