FMN1

Across TCGA patient cohorts, FMN1 mutation is significantly associated with the RNA expression of many other genes, with 6,216 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FMN1-associated genes across cancer lineages are MTATP6P21, ING2, and TIMM21. Each is linked with FMN1 in more than 3 cancer types. Because this analysis shows association rather than direction, both FMN1-to-partner and partner-to-FMN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTATP6P21 grouped by FMN1-low versus FMN1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FMN1→partner) and Y-score (partner→FMN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MTATP6P21 →	+0.138	+1.230	<.001	.009	3	4
STAD	ING2 →	+0.525	+3.182	.001	.009	3	3
UCEC	TIMM21 →	+0.544	+2.949	<.001	<.001	3	3
UCEC	COX16 →	+0.402	+1.440	<.001	<.001	3	3
COAD	RPA2P2 →	+0.350	+3.710	.008	.007	3	3
SARC	IGHD4-17 →	+1.993	+5.345	<.001	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,216 associations by consensus.

MTATP6P21 by FMN1 expression — UCEC

Explore this box plot interactively →