FMC1

Across TCGA patient cohorts, FMC1 protein abundance is significantly associated with the RNA expression of many other genes, with 9,311 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible FMC1-associated genes across cancer lineages are ARHGAP9, ALOX5, and GAS1. Each is linked with FMC1 in more than 4 cancer types. Because this analysis shows association rather than direction, both FMC1-to-partner and partner-to-FMC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FMC1 versus ARHGAP9 in BRCA, with a Pearson correlation of -0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FMC1→partner) and Y-score (partner→FMC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ARHGAP9 →	-0.769	-0.535	<.001	.001	3	5
OV	ALOX5 →	-1.292	-0.554	<.001	<.001	3	5
COAD	GAS1 →	-1.473	-0.351	.008	.009	3	5
GBM	CCN4 →	-1.275	-0.552	.003	.003	3	5
OV	ADAM19 →	-1.070	-0.384	<.001	.002	3	5
OV	PPP1R18 →	-1.092	-0.555	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,311 associations by consensus.

FMC1 vs ARHGAP9 — BRCA

Explore this scatter interactively →