FMC1

Across TCGA cell cohorts, FMC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,558 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FMC1-associated GO terms across cancer lineages are Mitochondrial proton-transporting ATP synthase complex assembly, Proton-transporting ATP synthase complex assembly, and Proton-transporting two-sector ATPase complex assembly. Each is linked with FMC1 in more than 16 cancer types. Because this analysis shows association rather than direction, both FMC1-to-partner and partner-to-FMC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial proton-transporting ATP synthase complex assembly grouped by FMC1-low versus FMC1-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FMC1→partner) and Y-score (partner→FMC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Mitochondrial proton-transporting ATP synthase complex assembly →	+0.133	+1.176	<.001	<.001	3	17
LUNG_SCLC	Proton-transporting ATP synthase complex assembly →	+0.133	+1.176	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Proton-transporting two-sector ATPase complex assembly →	+0.138	+1.189	<.001	<.001	3	17
KIDNEY	Surfactant homeostasis →	-0.197	-0.925	.004	.001	3	11
UPPER_AERODIGESTIVE_TRACT	Mitochondrial respiratory chain complex assembly →	+0.082	+1.105	.004	.003	2	12
BREAST	tRNA threonylcarbamoyladenosine modification →	+0.079	+0.816	.004	.002	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,558 associations by consensus.

Mitochondrial proton-transporting ATP synthase complex assembly by FMC1 expression — LUNG_SCLC

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