FLT3LG

Across TCGA patient cohorts, FLT3LG RNA expression is significantly associated with the go_rna of many other GO terms, with 7,171 significant associations in total. STAD shows the largest number of these associations.

The most reproducible FLT3LG-associated GO terms across cancer lineages are Negative T cell selection, Negative regulation of viral genome replication, and Alpha-beta T cell activation. Each is linked with FLT3LG in more than 28 cancer types. Because this analysis shows association rather than direction, both FLT3LG-to-partner and partner-to-FLT3LG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative T cell selection grouped by FLT3LG-low versus FLT3LG-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FLT3LG→partner) and Y-score (partner→FLT3LG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Negative T cell selection →	+0.108	+0.562	<.001	<.001	3	29
UCS	Negative regulation of viral genome replication →	+0.066	+0.561	.001	.002	3	28
CHOL	Alpha-beta T cell activation →	+0.084	+1.374	<.001	.001	3	28
STAD	Negative regulation of viral process →	+0.059	+0.383	<.001	<.001	3	28
STAD	Regulation of viral process →	+0.058	+0.391	<.001	<.001	3	28
STAD	Regulation of T cell apoptotic process →	+0.071	+0.495	<.001	<.001	3	27

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,171 associations by consensus.

Negative T cell selection by FLT3LG expression — STAD

Explore this box plot interactively →