FLT3LG

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FLT3LG protein abundance is significantly associated with the RNA expression of many other genes, with 19,463 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FLT3LG-associated genes across cancer lineages are MXRA5, COL1A1, and MRC2. Each is linked with FLT3LG in more than 8 cancer types. Because this analysis shows association rather than direction, both FLT3LG-to-partner and partner-to-FLT3LG results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FLT3LG versus MXRA5 in OV, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FLT3LG→partner) and Y-score (partner→FLT3LG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVMXRA5 →+1.979+0.608<.001<.00139
OVCOL1A1 →+2.263+0.561<.001<.00139
OVMRC2 →+1.202+0.688<.001<.00139
OVDSE →+0.835+0.611<.001<.00139
OVLOX →+1.668+0.560<.001<.00139
OVFN1 →+2.447+0.546<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 19,463 associations by consensus.

FLT3LG vs MXRA5 — OV

Per-sample scatter of FLT3LG vs MXRA5 in OV (Pearson r = 0.49).

Explore this scatter interactively →

Exploration