FLT3LG

Across TCGA patient cohorts, FLT3LG mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FLT3LG-associated genes across cancer lineages are DC and lymphatic Endothelial cells. Each is linked with FLT3LG in more than 1 cancer types. Because this analysis shows association rather than direction, both FLT3LG-to-partner and partner-to-FLT3LG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DC grouped by FLT3LG-low versus FLT3LG-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FLT3LG→partner) and Y-score (partner→FLT3LG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DC →	+0.020	+1.938	.034	.029	3	1
UCEC	lymphatic Endothelial cells →	-0.025	-3.281	.025	.010	2	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

DC by FLT3LG expression — UCEC

Explore this box plot interactively →