FLT3LG

Across TCGA cell cohorts, FLT3LG mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FLT3LG-associated genes across cancer lineages are MMP27, KRTAP12-3, and ETDB. Each is linked with FLT3LG in more than 1 cancer types. Because this analysis shows association rather than direction, both FLT3LG-to-partner and partner-to-FLT3LG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MMP27 grouped by FLT3LG-low versus FLT3LG-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FLT3LG→partner) and Y-score (partner→FLT3LG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	MMP27 →	+0.019	+4.969	<.001	.003	3	1
BLOOD_Leukemia	KRTAP12-3 →	+0.061	+4.539	<.001	.007	3	1
BLOOD_Leukemia	ETDB →	+0.054	+4.551	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

MMP27 by FLT3LG expression — BLOOD_Leukemia

Explore this box plot interactively →