FLRT1

Across TCGA patient cohorts, FLRT1 mutation is significantly associated with the RNA expression of many other genes, with 1,286 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FLRT1-associated genes across cancer lineages are TRAJ48, OR10G9, and RN7SL346P. Each is linked with FLRT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FLRT1-to-partner and partner-to-FLRT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRAJ48 grouped by FLRT1-low versus FLRT1-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FLRT1→partner) and Y-score (partner→FLRT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	TRAJ48 →	+0.670	+5.177	<.001	.007	3	2
SKCM	OR10G9 →	+0.008	+4.647	<.001	.001	3	2
SKCM	RN7SL346P →	+0.034	+3.716	<.001	.001	3	2
KIRP	ENSAP3 →	+0.154	+6.082	.001	<.001	3	2
KIRP	TRDJ4 →	+0.501	+5.301	<.001	.003	3	2
UCEC	DUSP15 →	-0.674	-2.514	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,286 associations by consensus.

TRAJ48 by FLRT1 expression — BLCA

Explore this box plot interactively →