FLRT1

Across TCGA pan-cancer cohorts, FLRT1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated FLRT1 data layer compared with 10 for mutation status.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher FLRT1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated FLRT1 expression acts as an unfavorable survival marker, although some lineages such as UCS and LGG show a favorable association.

UCS, LGG, and LIHC are the cancer types where FLRT1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	DFS	Tertile	II,III,IV	0.628	0.124	<.001	72	view →
LGG	DFS	Median	All	0.817	0.641	<.001	51	view →
LIHC	DFS	Median	All	0.455	0.622	<.001	46	view →
ESCA	OS	Quartile	III,IV	0.765	0.424	.008	40	view →
COAD	OS	Median	All	0.813	0.919	.004	39	view →
MESO	DFS	Tertile	All	0.219	0.660	.012	34	view →
ACC	OS	Tertile	III,IV	0.662	0.162	.003	31	view →
CESC	DFS	Quartile	All	0.769	0.913	.004	30	view →
KIRC	DFS	Quartile	III,IV	0.502	0.733	.002	24	view →
READ	DFS	Quartile	All	0.835	0.284	.005	16	view →
PRAD	DFS	Tertile	All	0.899	0.957	.003	16	view →
LUAD	DFS	Quartile	All	0.184	0.395	.006	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

FLRT1–UCS (DFS)

Open the UCS breakdown →