FLOT1

Across TCGA pan-cancer cohorts, FLOT1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated FLOT1 data layer compared with 23 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher FLOT1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated FLOT1 expression acts as an unfavorable survival marker.

LUAD, CCRCC, and LSCC are the cancer types where FLOT1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Tertile	III,IV	0.207	0.734	.001	57	view →
CCRCC	OS	Median	II,III,IV	0.630	0.875	.006	8	view →
LSCC	DFS	Median	II,III,IV	0.588	0.807	.028	4	view →
PDAC	OS	Median	All	0.758	0.930	.007	4	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

FLOT1–LUAD (OS)

Open the LUAD breakdown →