FLOT1

Across TCGA patient cohorts, FLOT1 protein abundance is significantly associated with the RNA expression of many other genes, with 12,091 significant associations in total. OV shows the largest number of these associations.

The most reproducible FLOT1-associated genes across cancer lineages are FLOT2, PIGS, and PHF12. Each is linked with FLOT1 in more than 6 cancer types. Because this analysis shows association rather than direction, both FLOT1-to-partner and partner-to-FLOT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FLOT1 versus FLOT2 in OV, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FLOT1→partner) and Y-score (partner→FLOT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	FLOT2 →	+0.686	+0.307	<.001	<.001	3	7
BRCA	PIGS →	+0.613	+0.299	<.001	<.001	3	4
BRCA	PHF12 →	+0.848	+0.521	<.001	<.001	3	3
HNSC	POLM →	+0.531	+0.208	.001	<.001	3	3
COAD	WBP2 →	+0.518	+0.219	.005	.007	3	3
BRCA	SLC46A1 →	+0.484	+0.313	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,091 associations by consensus.

FLOT1 vs FLOT2 — OV

Explore this scatter interactively →