FLOT1

Across TCGA cell cohorts, FLOT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,072 significant associations in total. BONE shows the largest number of these associations.

The most reproducible FLOT1-associated GO terms across cancer lineages are Caveola assembly, MAPK cascade, and Positive regulation of stress-activated protein kinase signaling cascade. Each is linked with FLOT1 in more than 8 cancer types. Because this analysis shows association rather than direction, both FLOT1-to-partner and partner-to-FLOT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caveola assembly grouped by FLOT1-low versus FLOT1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FLOT1→partner) and Y-score (partner→FLOT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Caveola assembly →	+0.178	+1.748	<.001	<.001	3	9
BONE	MAPK cascade →	+0.073	+1.151	<.001	<.001	3	9
BONE	Positive regulation of stress-activated protein kinase signaling cascade →	+0.166	+1.343	<.001	<.001	3	8
URINARY_TRACT	Regulation of Golgi inheritance →	+0.157	+1.041	.002	.005	3	8
BONE	Negative regulation of cell killing →	+0.173	+1.164	<.001	<.001	3	8
URINARY_TRACT	Regulation of G1/S transition of mitotic cell cycle →	+0.072	+1.281	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,072 associations by consensus.

Caveola assembly by FLOT1 expression — BONE

Explore this box plot interactively →