FLNC-AS1

Across TCGA pan-cancer cohorts, FLNC-AS1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated FLNC-AS1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher FLNC-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated FLNC-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCS and LAML show a favorable association.

ACC, KIRC, and KICH are the cancer types where FLNC-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Tertile	All	0.128	0.706	<.001	129	view →
KIRC	OS	Tertile	All	0.520	0.678	<.001	74	view →
KICH	DFS	Tertile	All	0.043	0.971	<.001	70	view →
UVM	DFS	Tertile	All	0.469	0.788	.004	69	view →
LUAD	DFS	Quartile	IV	0.292	0.814	<.001	62	view →
LGG	DFS	Median	All	0.634	0.829	<.001	54	view →
THCA	DFS	Tertile	IV	0.075	0.807	<.001	54	view →
UCEC	DFS	Tertile	All	0.470	0.712	.005	48	view →
UCS	DFS	Tertile	III,IV	0.490	0.157	.009	46	view →
KIRP	DFS	Quartile	All	0.564	0.794	<.001	38	view →
LAML	DFS	Quartile	All	0.729	0.378	.015	36	view →
LIHC	DFS	Tertile	All	0.404	0.575	.010	27	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

FLNC-AS1–ACC (OS)

Open the ACC breakdown →