FLNC-AS1

Across TCGA pan-cancer cohorts, FLNC-AS1 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of FLNC-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where FLNC-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types FLNC-AS1 is over-expressed in tumor, although a few such as BRCA and UCEC show the opposite, repressed pattern.

BRCA, COAD, and UCEC are the cancer types where FLNC-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FLNC-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	II,III,IV	−0.081	<.001	6	view →
COAD	Female	II,III,IV	+0.283	<.001	5	view →
UCEC	All	All	−0.271	.003	4	view →
BLCA	All	All	−0.652	.013	3	view →
KIRC	All	II,III,IV	+0.074	.044	2	view →
KICH	Male	II,III,IV	+0.181	.037	1	view →
LIHC	All	All	+0.031	.016	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

FLNC-AS1–BRCA

Open the BRCA breakdown →