FLNB

Across TCGA patient cohorts, FLNB RNA expression is significantly associated with the protein abundance of many other proteins, with 13,465 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible FLNB-associated proteins across cancer lineages are FLNB_S2107, FLNB_S2497, and NIBAN2. Each is linked with FLNB in more than 5 cancer types. Because this analysis shows association rather than direction, both FLNB-to-partner and partner-to-FLNB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FLNB versus FLNB_S2107 in GBM, with a Pearson correlation of 0.62.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FLNB→partner) and Y-score (partner→FLNB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	FLNB_S2107 →	+0.826	+0.746	<.001	<.001	3	6
BRCA	FLNB_S2497 →	+0.753	+1.376	<.001	<.001	3	6
PDAC	NIBAN2 →	+0.383	+0.956	<.001	<.001	3	6
HNSC	ZNF185 →	+0.717	+0.882	<.001	<.001	3	5
HNSC	FLNB_S1505 →	+1.010	+0.685	<.001	.008	3	5
HNSC	FLNB_S2113 →	+0.802	+0.947	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,465 associations by consensus.

FLNB vs FLNB_S2107 — GBM

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