FLNB

Across TCGA patient cohorts, FLNB protein abundance is significantly associated with the RNA expression of many other genes, with 16,583 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FLNB-associated genes across cancer lineages are FLNB-AS1, PPP1R13L, and UACA. Each is linked with FLNB in more than 7 cancer types. Because this analysis shows association rather than direction, both FLNB-to-partner and partner-to-FLNB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FLNB versus FLNB-AS1 in PDAC, with a Pearson correlation of 0.81.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FLNB→partner) and Y-score (partner→FLNB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	FLNB-AS1 →	+0.953	+0.575	<.001	<.001	3	8
LSCC	PPP1R13L →	+0.727	+0.390	<.001	<.001	3	5
CCRCC	UACA →	+0.624	+0.352	<.001	<.001	3	5
LSCC	TGFBR2 →	+0.728	+0.345	<.001	.001	3	5
GBM	KCNA2 →	-1.082	-0.467	<.001	<.001	3	5
GBM	CAV1 →	+1.371	+0.403	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,583 associations by consensus.

FLNB vs FLNB-AS1 — PDAC

Explore this scatter interactively →