FLNB

Across TCGA cell cohorts, FLNB RNA expression is significantly associated with the go_rna of many other GO terms, with 4,402 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible FLNB-associated GO terms across cancer lineages are Positive regulation of plasma membrane repair, Positive regulation of leukocyte migration, and Positive regulation of leukocyte chemotaxis. Each is linked with FLNB in more than 13 cancer types. Because this analysis shows association rather than direction, both FLNB-to-partner and partner-to-FLNB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of plasma membrane repair grouped by FLNB-low versus FLNB-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FLNB→partner) and Y-score (partner→FLNB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of plasma membrane repair →	+0.232	+1.086	.002	.004	3	14
LUNG_NSCLC_LUSC	Positive regulation of leukocyte migration →	+0.125	+1.714	.001	.002	3	11
CNS	Positive regulation of leukocyte chemotaxis →	+0.089	+1.195	.001	.001	2	12
BONE	Regulation of macrophage fusion →	+0.186	+1.150	.002	.002	3	11
BONE	Positive regulation of macrophage fusion →	+0.186	+1.150	.002	.002	3	11
BONE	Wound healing →	+0.091	+0.967	.001	.001	2	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,402 associations by consensus.

Positive regulation of plasma membrane repair by FLNB expression — BONE

Explore this box plot interactively →