FLG2

Across TCGA patient cohorts, FLG2 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,005 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FLG2-associated proteins across cancer lineages are COL1A1, COL1A2, and COL5A2. Each is linked with FLG2 in more than 3 cancer types. Because this analysis shows association rather than direction, both FLG2-to-partner and partner-to-FLG2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FLG2 versus COL1A1 in BRCA, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FLG2→partner) and Y-score (partner→FLG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	COL1A1 →	+0.828	+0.053	<.001	<.001	3	3
BRCA	COL1A2 →	+0.967	+0.055	<.001	<.001	3	3
BRCA	COL5A2 →	+0.664	+0.048	<.001	<.001	3	3
BRCA	DNM1 →	+0.579	+0.042	<.001	.009	3	3
UCEC	GMDS_S10 →	-0.607	-0.432	.001	.002	3	3
UCEC	HOOK2 →	-0.337	-0.513	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,005 associations by consensus.

FLG2 vs COL1A1 — BRCA

Explore this scatter interactively →