FLACC1

Across TCGA cell cohorts, FLACC1 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible FLACC1-associated genes across cancer lineages are RESP18, GPR33, and OR14A2. Each is linked with FLACC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FLACC1-to-partner and partner-to-FLACC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RESP18 grouped by FLACC1-low versus FLACC1-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FLACC1→partner) and Y-score (partner→FLACC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	RESP18 →	+0.072	+5.169	<.001	.005	3	2
SKIN	GPR33 →	+0.012	+4.977	.002	.007	3	1
BREAST	OR14A2 →	+0.032	+5.169	<.001	.005	3	1
LUNG_NSCLC_LUAD	CST11 →	+0.151	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	RNASE9 →	+0.022	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	OR1P1 →	+0.058	+4.887	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

RESP18 by FLACC1 expression — BREAST

Explore this box plot interactively →