FLACC1

Across TCGA pan-cancer cohorts, FLACC1 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of FLACC1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where FLACC1 RNA is repressed in tumor relative to normal tissue. In most cancer types FLACC1 is over-expressed in tumor, although a few such as KIRC and KICH show the opposite, repressed pattern.

KIRC, KICH, and LUSC are the cancer types where FLACC1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FLACC1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	II,III,IV	−0.403	<.001	11	view →
KICH	Male	All	−0.896	<.001	10	view →
LUSC	Male	II,III,IV	−1.140	<.001	8	view →
LUAD	All	III,IV	−0.976	<.001	8	view →
BLCA	Male	III,IV	−0.439	.005	8	view →
THCA	All	All	−0.297	.001	7	view →
KIRP	All	II,III,IV	−0.364	.004	6	view →
LIHC	Female	All	+0.141	.002	4	view →
CHOL	Male	All	+0.210	.010	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

FLACC1–KIRC

Open the KIRC breakdown →