FKTN

Across TCGA patient cohorts, FKTN mutation is significantly associated with the RNA expression of many other genes, with 1,522 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FKTN-associated genes across cancer lineages are RN7SL479P, RNA5SP183, and RNU6-287P. Each is linked with FKTN in more than 1 cancer types. Because this analysis shows association rather than direction, both FKTN-to-partner and partner-to-FKTN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL479P grouped by FKTN-low versus FKTN-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FKTN→partner) and Y-score (partner→FKTN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RN7SL479P →	+0.221	+5.418	<.001	.005	3	2
STAD	RNA5SP183 →	+0.322	+3.981	.004	.005	3	2
HNSC	RNU6-287P →	+0.548	+5.182	<.001	.007	3	2
SKCM	PPP1R2P5 →	+0.035	+4.302	<.001	.007	3	2
BRCA	MIR6853 →	+0.242	+8.057	<.001	.005	3	1
BRCA	MIR7159 →	+0.479	+5.317	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,522 associations by consensus.

RN7SL479P by FKTN expression — CESC

Explore this box plot interactively →