FKBP8

Across TCGA patient cohorts, FKBP8 protein abundance is significantly associated with the RNA expression of many other genes, with 13,805 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FKBP8-associated genes across cancer lineages are SKA3, HJURP, and MTFR2. Each is linked with FKBP8 in more than 5 cancer types. Because this analysis shows association rather than direction, both FKBP8-to-partner and partner-to-FKBP8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FKBP8 versus SKA3 in UCEC, with a Pearson correlation of 0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FKBP8→partner) and Y-score (partner→FKBP8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SKA3 →	+0.824	+0.340	<.001	<.001	3	6
BRCA	HJURP →	+1.083	+0.277	<.001	<.001	3	5
BRCA	MTFR2 →	+0.867	+0.245	<.001	<.001	3	5
BRCA	FANCA →	+0.645	+0.245	<.001	.001	3	5
BRCA	ARHGAP11A →	+0.798	+0.240	<.001	.001	3	5
LSCC	ASPM →	+1.141	+0.233	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,805 associations by consensus.

FKBP8 vs SKA3 — UCEC

Explore this scatter interactively →