FKBP6

Across TCGA pan-cancer cohorts, FKBP6 Mutation is linked to patient survival in 7 of 34 cancer types, making it a survival-associated FKBP6 data layer compared with 19 for mass-spec protein and 1 for mass-spec protein.

The strongest signal is observed in thymoma (THYM), where higher FKBP6 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated FKBP6 expression acts as an unfavorable survival marker.

THYM, LUSC, and LIHC are the cancer types where FKBP6 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THYM	OS	Median	III,IV	0.103	0.944	<.001	42	view →
LUSC	OS	Median	All	0.164	0.659	.022	15	view →
LIHC	OS	Median	All	0.015	0.784	<.001	12	view →
GBM	DFS	Median	All	0.075	0.296	<.001	6	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
LGG	DFS	Median	All	0.110	0.833	<.001	6	view →
SKCM	DFS	Median	All	0.084	0.211	.010	4	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

FKBP6–THYM (OS)

Open the THYM breakdown →