FKBP4

Across TCGA pan-cancer cohorts, FKBP4 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated FKBP4 data layer compared with 26 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher FKBP4 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated FKBP4 expression acts as an unfavorable survival marker, although some lineages such as PDAC and LSCC show a favorable association.

CCRCC, PDAC, and LSCC are the cancer types where FKBP4 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Quartile	III,IV	0.430	0.876	.001	65	view →
PDAC	DFS	Quartile	All	0.596	0.265	.005	26	view →
LSCC	DFS	Quartile	All	1.000	0.837	.004	13	view →
GBM	OS	Quartile	All	0.773	0.374	<.001	8	view →
UCEC	OS	Median	III,IV	0.884	0.492	.031	4	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

FKBP4–CCRCC (OS)

Open the CCRCC breakdown →