FKBP4

Across TCGA cell cohorts, FKBP4 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,425 significant associations in total. BONE shows the largest number of these associations.

The most reproducible FKBP4-associated GO terms across cancer lineages are DNA replication initiation, Positive regulation of DNA metabolic process, and Regulation of DNA repair. Each is linked with FKBP4 in more than 15 cancer types. Because this analysis shows association rather than direction, both FKBP4-to-partner and partner-to-FKBP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication initiation grouped by FKBP4-low versus FKBP4-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FKBP4→partner) and Y-score (partner→FKBP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	DNA replication initiation →	+0.240	+1.440	<.001	.002	3	16
BONE	Positive regulation of DNA metabolic process →	+0.074	+0.999	<.001	<.001	3	15
SOFT_TISSUE	Regulation of DNA repair →	+0.075	+0.993	<.001	<.001	3	14
BONE	rRNA transcription →	+0.149	+1.341	<.001	.005	3	14
BONE	DNA replication →	+0.158	+1.488	<.001	.001	3	14
UPPER_AERODIGESTIVE_TRACT	Transcription initiation at RNA polymerase III promoter →	+0.117	+1.065	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,425 associations by consensus.

DNA replication initiation by FKBP4 expression — BONE

Explore this box plot interactively →