FKBP2

Across TCGA patient cohorts, FKBP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,163 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible FKBP2-associated GO terms across cancer lineages are Positive regulation of mRNA 3'-end processing, Establishment of mitotic sister chromatid cohesion, and Protein K29-linked deubiquitination. Each is linked with FKBP2 in more than 26 cancer types. Because this analysis shows association rather than direction, both FKBP2-to-partner and partner-to-FKBP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of mRNA 3'-end processing grouped by FKBP2-low versus FKBP2-high in DLBC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FKBP2→partner) and Y-score (partner→FKBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	Positive regulation of mRNA 3'-end processing →	-0.087	-1.015	<.001	<.001	3	27
DLBC	Establishment of mitotic sister chromatid cohesion →	-0.098	-0.927	<.001	<.001	3	27
TGCT	Protein K29-linked deubiquitination →	-0.080	-0.460	<.001	<.001	3	27
ESCA	Regulation of endoplasmic reticulum tubular network organization →	-0.061	-0.507	<.001	<.001	3	26
CHOL	Intra-Golgi vesicle-mediated transport →	-0.059	-0.806	.002	.002	2	26
DLBC	Regulation of Golgi organization →	-0.067	-1.032	<.001	<.001	3	25

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,163 associations by consensus.

Positive regulation of mRNA 3'-end processing by FKBP2 expression — DLBC

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