FKBP2

Across TCGA cell cohorts, FKBP2 protein abundance is significantly associated with the go_rna of many other GO terms, with 1,445 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible FKBP2-associated GO terms across cancer lineages are Regulation of synaptic membrane adhesion, Endosome transport via multivesicular body sorting pathway, and Late endosome to vacuole transport. Each is linked with FKBP2 in more than 5 cancer types. Because this analysis shows association rather than direction, both FKBP2-to-partner and partner-to-FKBP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of synaptic membrane adhesion grouped by FKBP2-low versus FKBP2-high in LARGE_INTESTINE.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FKBP2→partner) and Y-score (partner→FKBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Regulation of synaptic membrane adhesion →	-0.838	-0.571	.008	.004	2	6
LUNG_SCLC	Endosome transport via multivesicular body sorting pathway →	+0.089	+1.090	<.001	<.001	3	5
LUNG_SCLC	Late endosome to vacuole transport →	+0.084	+0.942	<.001	.003	3	5
PANCREAS	AMP salvage →	-0.189	-1.057	.001	<.001	3	5
PANCREAS	rRNA processing →	-0.091	-1.006	.001	.001	3	5
PANCREAS	Maturation of SSU-rRNA →	-0.100	-1.036	.002	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,445 associations by consensus.

Regulation of synaptic membrane adhesion by FKBP2 expression — LARGE_INTESTINE

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