FKBP1B

Across TCGA pan-cancer cohorts, FKBP1B mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated FKBP1B data layer compared with 23 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher FKBP1B mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated FKBP1B expression acts as an unfavorable survival marker, although some lineages such as GBM show a favorable association.

UCEC, LSCC, and LUAD are the cancer types where FKBP1B mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Quartile	II,III,IV	0.314	1.000	.012	36	view →
LSCC	OS	Median	III,IV	0.485	1.000	.003	13	view →
LUAD	OS	Tertile	III,IV	0.218	0.840	.032	6	view →
PDAC	OS	Median	IV	0.491	0.836	.024	3	view →
GBM	DFS	Quartile	All	0.889	0.641	.047	1	view →
CCRCC	OS	Tertile	II,III,IV	0.520	1.000	.031	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

FKBP1B–UCEC (OS)

Open the UCEC breakdown →