FKBP1A

Across TCGA pan-cancer cohorts, FKBP1A mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated FKBP1A data layer compared with 26 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher FKBP1A mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated FKBP1A expression acts as an unfavorable survival marker, although some lineages such as PDAC show a favorable association.

UCEC, LSCC, and CCRCC are the cancer types where FKBP1A mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	II,III,IV	0.446	0.946	.001	24	view →
LSCC	DFS	Median	II,III,IV	0.485	1.000	.006	20	view →
CCRCC	DFS	Median	III,IV	0.809	1.000	.012	12	view →
LUAD	DFS	Median	II,III,IV	0.788	0.919	.022	4	view →
PDAC	DFS	Median	All	0.878	0.713	.017	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

FKBP1A–UCEC (DFS)

Open the UCEC breakdown →