FKBP1A

Across TCGA cell cohorts, FKBP1A RNA expression is significantly associated with the go_rna of many other GO terms, with 4,107 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible FKBP1A-associated GO terms across cancer lineages are Positive regulation of protein localization to endoplasmic reticulum, Protein import into peroxisome membrane, and Regulation of peroxisome organization. Each is linked with FKBP1A in more than 12 cancer types. Because this analysis shows association rather than direction, both FKBP1A-to-partner and partner-to-FKBP1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of protein localization to endoplasmic reticulum grouped by FKBP1A-low versus FKBP1A-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FKBP1A→partner) and Y-score (partner→FKBP1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Positive regulation of protein localization to endoplasmic reticulum →	+0.119	+0.663	.001	.007	2	13
LUNG_NSCLC_LUSC	Protein import into peroxisome membrane →	+0.115	+0.958	.009	.007	3	12
URINARY_TRACT	Regulation of peroxisome organization →	+0.238	+1.277	<.001	<.001	3	11
KIDNEY	Regulation of protein localization to endoplasmic reticulum →	+0.113	+0.663	.001	.007	2	12
STOMACH	Caveolin-mediated endocytosis →	+0.185	+0.803	<.001	.003	3	11
SOFT_TISSUE	Protein lipoylation →	-0.138	-1.183	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,107 associations by consensus.

Positive regulation of protein localization to endoplasmic reticulum by FKBP1A expression — KIDNEY

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