FKBP14

Across TCGA pan-cancer cohorts, FKBP14 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated FKBP14 data layer compared with 28 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher FKBP14 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated FKBP14 expression acts as an unfavorable survival marker.

HNSC, STAD, and SKCM are the cancer types where FKBP14 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	II,III,IV	0.058	0.743	<.001	42	view →
STAD	OS	Median	All	0.184	0.730	.001	33	view →
SKCM	DFS	Median	All	0.046	0.738	<.001	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

FKBP14–HNSC (OS)

Open the HNSC breakdown →