FKBP14

Across TCGA pan-cancer cohorts, FKBP14 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated FKBP14 data layer compared with 28 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher FKBP14 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated FKBP14 expression acts as an unfavorable survival marker.

LSCC, PDAC, and LUAD are the cancer types where FKBP14 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Tertile	All	0.659	0.904	.008	18	view →
PDAC	OS	Median	II,III,IV	0.711	0.922	.003	14	view →
LUAD	OS	Quartile	All	0.747	0.967	.001	9	view →
HNSC	DFS	Tertile	IV	0.478	0.878	.003	8	view →
CCRCC	DFS	Median	II,III,IV	0.128	0.942	.007	6	view →
UCEC	OS	Median	II,III,IV	0.620	1.000	.011	6	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

FKBP14–LSCC (DFS)

Open the LSCC breakdown →