FKBP14

Across TCGA patient cohorts, FKBP14 mutation is significantly associated with the RNA expression of many other genes, with 2,381 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FKBP14-associated genes across cancer lineages are TMEM225, ZIC3, and RNU6-1175P. Each is linked with FKBP14 in more than 1 cancer types. Because this analysis shows association rather than direction, both FKBP14-to-partner and partner-to-FKBP14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TMEM225 grouped by FKBP14-low versus FKBP14-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FKBP14→partner) and Y-score (partner→FKBP14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	TMEM225 →	+0.091	+5.039	<.001	.008	3	2
READ	ZIC3 →	+0.035	+5.653	<.001	.003	3	1
READ	RNU6-1175P →	+0.604	+5.421	<.001	.005	3	1
READ	RN7SKP158 →	+0.254	+5.421	<.001	.005	3	1
READ	MED28P4 →	+0.398	+5.039	<.001	.008	3	1
READ	CDK4P1 →	+0.161	+5.421	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,381 associations by consensus.

TMEM225 by FKBP14 expression — READ

Explore this box plot interactively →