FKBP10

Across TCGA pan-cancer cohorts, FKBP10 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated FKBP10 data layer compared with 25 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher FKBP10 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated FKBP10 expression acts as an unfavorable survival marker.

CCRCC, PDAC, and HNSC are the cancer types where FKBP10 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Tertile	All	0.770	0.986	<.001	122	view →
PDAC	DFS	Tertile	All	0.656	0.846	.017	16	view →
HNSC	OS	Median	IV	0.614	0.843	.025	10	view →
GBM	DFS	Tertile	All	0.665	0.832	.015	5	view →
UCEC	OS	Tertile	II,III,IV	0.628	1.000	.041	4	view →
LSCC	DFS	Median	All	0.461	0.861	.028	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

FKBP10–CCRCC (OS)

Open the CCRCC breakdown →