FKBP10

Across TCGA cell cohorts, FKBP10 mutation is significantly associated with the RNA expression of many other genes, with 64 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FKBP10-associated genes across cancer lineages are ASB17, OR2M4, and C12orf40. Each is linked with FKBP10 in more than 1 cancer types. Because this analysis shows association rather than direction, both FKBP10-to-partner and partner-to-FKBP10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASB17 grouped by FKBP10-low versus FKBP10-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FKBP10→partner) and Y-score (partner→FKBP10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	ASB17 →	+0.017	+4.807	<.001	.003	3	1
OVARY	OR2M4 →	+0.070	+4.700	<.001	.002	3	1
OVARY	C12orf40 →	+0.011	+4.029	<.001	.009	3	1
OVARY	OR2H1 →	+0.019	+4.029	.003	.009	3	1
OVARY	RBMY1A1 →	+0.107	+4.807	<.001	.003	3	1
OVARY	OR2L8 →	+0.038	+4.450	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 64 associations by consensus.

ASB17 by FKBP10 expression — OVARY

Explore this box plot interactively →