FKBP10

Across TCGA cell cohorts, FKBP10 mutation is significantly associated with the mutation status of many other genes, with 4,535 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FKBP10-associated genes across cancer lineages are CREBBP, GCN1, and CACNA1I. Each is linked with FKBP10 in more than 4 cancer types. Because this analysis shows association rather than direction, both FKBP10-to-partner and partner-to-FKBP10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CREBBP grouped by FKBP10-low versus FKBP10-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FKBP10→partner) and Y-score (partner→FKBP10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	CREBBP →	+2.942	+4.025	.009	.009	1	5
LARGE_INTESTINE	GCN1 →	+1.691	+2.479	.008	.008	1	4
OVARY	CACNA1I →	+3.562	+4.684	.002	.002	1	4
SOFT_TISSUE	CHD8 →	+5.502	+5.502	.003	.003	1	4
OVARY	ABCC3 →	+3.562	+4.684	.002	.002	1	4
SOFT_TISSUE	ADGRA2 →	+5.502	+5.502	.003	.003	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,535 associations by consensus.

CREBBP by FKBP10 expression — STOMACH

Explore this box plot interactively →