FIZ1

Across TCGA cell cohorts, FIZ1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,376 significant associations in total. BONE shows the largest number of these associations.

The most reproducible FIZ1-associated GO terms across cancer lineages are Regulation of chromatin organization, mRNA alternative polyadenylation, and Positive regulation of intracellular steroid hormone receptor signaling pathway. Each is linked with FIZ1 in more than 14 cancer types. Because this analysis shows association rather than direction, both FIZ1-to-partner and partner-to-FIZ1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of chromatin organization grouped by FIZ1-low versus FIZ1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FIZ1→partner) and Y-score (partner→FIZ1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Regulation of chromatin organization →	+0.095	+0.695	<.001	.001	3	15
BONE	mRNA alternative polyadenylation →	+0.108	+1.108	<.001	<.001	3	14
STOMACH	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.167	+0.953	<.001	<.001	3	14
BONE	Epigenetic regulation of gene expression →	+0.098	+1.240	<.001	<.001	3	14
STOMACH	mRNA transcription →	+0.099	+0.930	.003	.002	3	14
STOMACH	Positive regulation of cell fate commitment →	+0.185	+0.864	.003	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,376 associations by consensus.

Regulation of chromatin organization by FIZ1 expression — SOFT_TISSUE

Explore this box plot interactively →