Across TCGA patient cohorts, FIRRE RNA expression is significantly associated with the protein abundance of many other proteins, with 11,249 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible FIRRE-associated proteins across cancer lineages are NOP2, NOP2_T195, and SHMT2. Each is linked with FIRRE in more than 4 cancer types. Because this analysis shows association rather than direction, both FIRRE-to-partner and partner-to-FIRRE results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FIRRE→partner) and Y-score (partner→FIRRE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	NOP2 →	+0.401	+0.637	.004	.001	3	5
LUAD	NOP2_T195 →	+0.565	+0.561	.001	.001	3	5
UCEC	SHMT2 →	+0.494	+1.258	.001	.003	3	4
LUAD	MCM2_S139 →	+0.486	+0.556	.002	<.001	3	4
CCRCC	MPI →	-0.449	-0.696	<.001	.001	3	4
UCEC	TIMELESS_S1173 →	+0.410	+1.132	.008	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,249 associations by consensus.

Exploration

FIRRE survival (RNA) · tumor vs normal (RNA) · all FIRRE data types