FILIP1

Across TCGA pan-cancer cohorts, FILIP1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated FILIP1 data layer compared with 22 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in glioblastoma multiforme (GBM), where higher FILIP1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated FILIP1 expression acts as an unfavorable survival marker, although some lineages such as PDAC and CCRCC show a favorable association.

GBM, PDAC, and CCRCC are the cancer types where FILIP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
GBM	DFS	Quartile	All	0.439	0.895	.010	11	view →
PDAC	DFS	Median	III,IV	0.936	0.382	.005	10	view →
CCRCC	DFS	Quartile	III,IV	0.787	0.429	.012	7	view →
LUAD	OS	Quartile	All	1.000	0.632	.015	3	view →
UCEC	DFS	Median	II,III,IV	0.809	1.000	.030	2	view →
LSCC	DFS	Tertile	All	0.903	0.989	.042	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

FILIP1–GBM (DFS)

Open the GBM breakdown →