FILIP1

Across TCGA patient cohorts, FILIP1 protein abundance is significantly associated with the RNA expression of many other genes, with 15,698 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FILIP1-associated genes across cancer lineages are CASQ2, LYVE1, and ABCA8. Each is linked with FILIP1 in more than 5 cancer types. Because this analysis shows association rather than direction, both FILIP1-to-partner and partner-to-FILIP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FILIP1 versus CASQ2 in HNSC, with a Pearson correlation of 0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FILIP1→partner) and Y-score (partner→FILIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CASQ2 →	+1.852	+0.501	<.001	<.001	3	6
COAD	LYVE1 →	+1.302	+0.925	<.001	<.001	3	6
UCEC	ABCA8 →	+1.445	+0.584	<.001	<.001	3	6
HNSC	HSPB7 →	+1.813	+0.556	<.001	<.001	3	6
COAD	DES →	+3.086	+0.844	<.001	<.001	3	6
HNSC	TMEM30A-DT →	+0.467	+0.978	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,698 associations by consensus.

FILIP1 vs CASQ2 — HNSC

Explore this scatter interactively →