FIGNL1

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FIGNL1 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,878 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FIGNL1-associated proteins across cancer lineages are POLD1, SMC2, and MCM2. Each is linked with FIGNL1 in more than 9 cancer types. Because this analysis shows association rather than direction, both FIGNL1-to-partner and partner-to-FIGNL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FIGNL1 versus POLD1 in GBM, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FIGNL1→partner) and Y-score (partner→FIGNL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMPOLD1 →+0.372+0.647<.001.001310
GBMSMC2 →+0.742+0.744<.001.00139
GBMMCM2 →+0.840+0.724<.001<.00139
OVMCM3 →+0.657+0.440.001.00439
LUADMCM4 →+0.639+0.793<.001<.00139
OVMCM5 →+0.735+0.708<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 17,878 associations by consensus.

FIGNL1 vs POLD1 — GBM

Per-sample scatter of FIGNL1 vs POLD1 in GBM (Pearson r = 0.45).

Explore this scatter interactively →

Exploration