FIGNL1

Across TCGA cell cohorts, FIGNL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,452 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FIGNL1-associated GO terms across cancer lineages are Osteoblast proliferation, Negative regulation of cell cycle process, and Negative regulation of G2/M transition of mitotic cell cycle. Each is linked with FIGNL1 in more than 18 cancer types. Because this analysis shows association rather than direction, both FIGNL1-to-partner and partner-to-FIGNL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Osteoblast proliferation grouped by FIGNL1-low versus FIGNL1-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FIGNL1→partner) and Y-score (partner→FIGNL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Osteoblast proliferation →	+0.216	+1.025	<.001	<.001	3	19
BONE	Negative regulation of cell cycle process →	+0.083	+0.966	.008	.005	3	17
PANCREAS	Negative regulation of G2/M transition of mitotic cell cycle →	+0.089	+1.154	<.001	<.001	3	17
BONE	DNA strand elongation →	+0.161	+0.766	.002	.007	3	17
UPPER_AERODIGESTIVE_TRACT	Mitotic G2/M transition checkpoint →	+0.127	+1.521	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	DNA replication →	+0.093	+0.999	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,452 associations by consensus.

Osteoblast proliferation by FIGNL1 expression — LUNG_SCLC

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