Across TCGA patient cohorts, FICD protein abundance is significantly associated with the RNA expression of many other genes, with 1,213 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible FICD-associated genes across cancer lineages are GPRASP2, METRNL, and ID1. Each is linked with FICD in more than 1 cancer types. Because this analysis shows association rather than direction, both FICD-to-partner and partner-to-FICD results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FICD→partner) and Y-score (partner→FICD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	GPRASP2 →	-0.764	-0.762	.001	.001	3	2
LUAD	METRNL →	+0.681	+0.530	<.001	.005	3	2
UCEC	ID1 →	-1.761	-0.431	.004	.007	3	2
BRCA	CLCN7 →	-0.615	-0.695	.007	.004	3	2
LSCC	DENND3 →	+0.598	+0.348	.005	.002	3	2
PDAC	NKD1 →	-1.092	-1.138	.002	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,213 associations by consensus.

Exploration

FICD survival (RNA) · tumor vs normal (RNA) · all FICD data types