Across TCGA patient cohorts, FICD mutation is significantly associated with the RNA expression of many other genes, with 2,315 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FICD-associated genes across cancer lineages are RN7SKP181, MIR769, and KRTAP4-5. Each is linked with FICD in more than 1 cancer types. Because this analysis shows association rather than direction, both FICD-to-partner and partner-to-FICD results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FICD→partner) and Y-score (partner→FICD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RN7SKP181 →	+0.107	+4.685	.001	.007	3	2
UCEC	MIR769 →	+0.349	+2.244	<.001	.001	3	2
CESC	KRTAP4-5 →	+0.087	+5.539	.001	.004	3	1
CESC	RN7SKP44 →	+0.228	+5.010	<.001	.009	3	1
CESC	RNU6-1214P →	+0.530	+5.306	<.001	.006	3	1
CESC	OR5G5P →	+0.127	+5.201	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,315 associations by consensus.

Exploration

FICD survival (RNA) · tumor vs normal (RNA) · all FICD data types